During pregnancy, it's common for women to experience sleep disturbances due to hormonal changes, discomfort, and anxiety. As a result, many pregnant women turn to over-the-counter sleep aids like Unisom to help them get a good night's rest. However, it's essential to understand the safety and efficacy of Unisom during pregnancy before using it. In this article, we'll delve into the world of Unisom and pregnancy, exploring the benefits, risks, and alternatives to help you make an informed decision.
What is Unisom?

Unisom is a brand of over-the-counter sleep aids that contain doxylamine or diphenhydramine as the primary active ingredients. These medications are antihistamines that can help induce sleep and relieve insomnia symptoms. Unisom is available in various forms, including tablets, capsules, and liquids, and is often used to treat occasional sleeplessness, restlessness, and insomnia.
Is Unisom Safe During Pregnancy?
The safety of Unisom during pregnancy is a topic of ongoing debate. While some studies suggest that doxylamine and diphenhydramine are relatively safe when used as directed, others raise concerns about potential risks to the fetus. The American College of Obstetricians and Gynecologists (ACOG) recommends that pregnant women use the lowest effective dose of Unisom for the shortest duration possible. However, it’s crucial to consult with your healthcare provider before taking Unisom or any other medication during pregnancy.
| Ingredient | Pregnancy Category |
|---|---|
| Doxylamine | B |
| Diphenhydramine | B |

In the table above, you can see that both doxylamine and diphenhydramine are classified as category B medications, which means that animal studies have not demonstrated a risk to the fetus, but there are no adequate and well-controlled studies in pregnant women. While this classification suggests that Unisom is relatively safe, it's essential to exercise caution and consult with your healthcare provider before using it.
Benefits and Risks of Unisom During Pregnancy

While Unisom may help alleviate sleep disturbances during pregnancy, it’s essential to weigh the benefits against the potential risks. Some benefits of using Unisom during pregnancy include:
- Relief from insomnia and sleeplessness
- Improved sleep quality and duration
- Reduced stress and anxiety
However, potential risks and side effects of using Unisom during pregnancy include:
- Drowsiness and sedation
- Dry mouth and throat
- Constipation
- Increased risk of birth defects (although the evidence is limited and inconclusive)
Alternatives to Unisom During Pregnancy
If you’re experiencing sleep disturbances during pregnancy, there are several alternatives to Unisom that you can try. Some of these alternatives include:
- Melatonin: a natural hormone that regulates sleep-wake cycles
- Valerian root: a natural herb that promotes relaxation and sleep
- Aromatherapy: essential oils like lavender and chamomile can promote relaxation and improve sleep quality
- Cognitive behavioral therapy for insomnia (CBT-I): a non-pharmacological approach that addresses underlying sleep habits and behaviors
Key Points
- Unisom is a brand of over-the-counter sleep aids that contain doxylamine or diphenhydramine
- The safety of Unisom during pregnancy is a topic of ongoing debate, and it's essential to consult with your healthcare provider before using it
- Non-pharmacological approaches, such as maintaining a consistent sleep schedule and creating a relaxing bedtime routine, can help manage sleep disturbances during pregnancy
- Alternatives to Unisom, such as melatonin, valerian root, and aromatherapy, can be effective in promoting relaxation and improving sleep quality
- Cognitive behavioral therapy for insomnia (CBT-I) is a non-pharmacological approach that addresses underlying sleep habits and behaviors
In conclusion, while Unisom may be a convenient solution for sleep disturbances during pregnancy, it's essential to approach its use with caution and consult with your healthcare provider before taking it. By prioritizing non-pharmacological approaches and exploring alternative solutions, you can promote a healthy and restful pregnancy.
Can I take Unisom during pregnancy?
+It’s essential to consult with your healthcare provider before taking Unisom during pregnancy. While some studies suggest that doxylamine and diphenhydramine are relatively safe, others raise concerns about potential risks to the fetus.
What are the alternatives to Unisom during pregnancy?
+Alternatives to Unisom during pregnancy include melatonin, valerian root, aromatherapy, and cognitive behavioral therapy for insomnia (CBT-I). These approaches can help promote relaxation and improve sleep quality without the potential risks associated with Unisom.
How can I manage sleep disturbances during pregnancy without medication?
+Non-pharmacological approaches, such as maintaining a consistent sleep schedule, creating a relaxing bedtime routine, and avoiding caffeine and electronics before bedtime, can help manage sleep disturbances during pregnancy. Additionally, techniques like deep breathing, progressive muscle relaxation, and mindfulness meditation can promote relaxation and improve sleep quality.